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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APLF
All Species:
3.03
Human Site:
S241
Identified Species:
8.33
UniProt:
Q8IW19
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IW19
NP_775816.1
511
56956
S241
R
Q
L
I
S
S
G
S
S
E
N
T
S
A
E
Chimpanzee
Pan troglodytes
XP_515525
303
34195
K60
E
E
S
T
I
S
S
K
E
M
P
Q
S
F
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538525
510
57035
S240
G
G
R
K
R
F
I
S
S
E
S
T
S
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D842
499
54950
G233
P
G
N
T
S
W
H
G
K
K
R
L
S
P
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514287
555
61656
L269
K
R
L
P
L
S
D
L
E
D
A
Q
E
N
E
Chicken
Gallus gallus
XP_419335
514
57457
E236
R
K
R
S
A
S
E
E
I
E
E
D
F
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001099159
262
29285
Y19
G
S
P
V
D
L
P
Y
G
E
T
V
L
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A8JR14
255
27987
G12
D
A
S
T
A
D
S
G
A
K
R
K
S
S
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788055
674
74378
E350
A
K
V
A
S
Y
A
E
D
E
Y
D
A
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.9
N.A.
72.2
N.A.
60
N.A.
N.A.
41.2
44.7
N.A.
23.4
N.A.
21.3
N.A.
N.A.
28.1
Protein Similarity:
100
58.9
N.A.
81.4
N.A.
74.7
N.A.
N.A.
57.2
61.8
N.A.
33
N.A.
31.5
N.A.
N.A.
43.7
P-Site Identity:
100
13.3
N.A.
46.6
N.A.
13.3
N.A.
N.A.
20
20
N.A.
6.6
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
20
N.A.
53.3
N.A.
20
N.A.
N.A.
40
40
N.A.
13.3
N.A.
40
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
12
23
0
12
0
12
0
12
0
12
23
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
12
12
12
0
12
12
0
23
0
0
23
% D
% Glu:
12
12
0
0
0
0
12
23
23
56
12
0
12
12
45
% E
% Phe:
0
0
0
0
0
12
0
0
0
0
0
0
12
12
0
% F
% Gly:
23
23
0
0
0
0
12
23
12
0
0
0
0
12
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
12
0
12
0
12
0
0
0
0
0
0
% I
% Lys:
12
23
0
12
0
0
0
12
12
23
0
12
0
0
0
% K
% Leu:
0
0
23
0
12
12
0
12
0
0
0
12
12
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% M
% Asn:
0
0
12
0
0
0
0
0
0
0
12
0
0
12
0
% N
% Pro:
12
0
12
12
0
0
12
0
0
0
12
0
0
12
0
% P
% Gln:
0
12
0
0
0
0
0
0
0
0
0
23
0
0
0
% Q
% Arg:
23
12
23
0
12
0
0
0
0
0
23
0
0
0
12
% R
% Ser:
0
12
23
12
34
45
23
23
23
0
12
0
56
12
23
% S
% Thr:
0
0
0
34
0
0
0
0
0
0
12
23
0
0
0
% T
% Val:
0
0
12
12
0
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
0
12
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _